Eric posted a link to Synergy:
synergy: [noun] a mutually advantageous conjunction of distinct elements
Synergy lets you easily share a single mouse and keyboard between multiple computers with different operating systems, each with its own display, without special hardware. It’s intended for users with multiple computers on their desk since each system uses its own monitor(s).
Redirecting the mouse and keyboard is as simple as moving the mouse off the edge of your screen. Synergy also merges the clipboards of all the systems into one, allowing cut-and-paste between systems. Furthermore, it synchronizes screen savers so they all start and stop together and, if screen locking is enabled, only one screen requires a password to unlock them all. Learn more about how it works.
The Mac OS X version is a little rough on the edges, but the application works as advertised. I’m running Synergy with my Quicksilver and my Quad PowerMac G5. I’ll probably hook up a PC laptop so I can be even more efficient while coding and doing web development. My Gigabit Ethernet hub is saturated with cables, so I have to use Mac OS X’s Internet Sharing to get the PC laptop onto the network. The Quad G5 comes with dual-Gigabit Ethernet ports so it makes providing additional network connections a snap!
If you have multiple computers on your desk and are looking for a way to reduce keyboard/mice clutter, check out Synergy!